Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | LSS | P48449 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694848 | 0.90 | HTR1B (0.61) | HTR1BCYP1A2CYP2D6TOP2AABCB11 | |
| SCHEMBL10695962 | 0.85 | HTR1B (0.62) | HTR1BCYP1A2CYP2D6TOP2AABCB11 | |
| SCHEMBL10692377 | 0.84 | L3MBTL1 (0.40) | HTR1BCYP1A2CYP2C19LMNATDP1 | |
| SCHEMBL29372017 | 0.84 | SLC2A1 (0.44) | HTR1BCYP1A2CYP2D6ABCB11LMNA | |
| SCHEMBL10693186 | 0.84 | HTR1B (0.47) | HTR1BCYP1A2DRD3TDP1MAOA | |
| SCHEMBL23089941 | 0.84 | SLC2A1 (0.44) | HTR1BCYP1A2CYP2D6ABCB11LMNA | |
| SCHEMBL10691295 | 0.84 | HTR1B (0.60) | HTR1BCYP1A2CYP2D6TOP2AABCB11 | |
| SCHEMBL10692799 | 0.84 | HTR1B (0.60) | HTR1BCYP1A2CYP2D6TOP2AABCB11 | |
| SCHEMBL10691756 | 0.84 | HTR1B (0.60) | HTR1BCYP1A2CYP2D6TOP2AABCB11 | |
| SCHEMBL10690273 | 0.84 | HTR1B (0.49) | HTR1BCYP1A2CYP2D6TOP2AABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |