Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | LSS | P48449 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691756 | 1.00 | HTR1B (0.60) | HTR1BCYP1A2CYP2D6ABCB11LMNA | |
| SCHEMBL10691295 | 1.00 | HTR1B (0.60) | HTR1BCYP1A2CYP2D6ABCB11LMNA | |
| SCHEMBL10695962 | 0.98 | HTR1B (0.62) | HTR1BCYP1A2CYP2D6ABCB11LMNA | |
| SCHEMBL10694848 | 0.93 | HTR1B (0.61) | HTR1BCYP1A2CYP2D6ABCB11LMNA | |
| SCHEMBL10692306 | 0.88 | HTR1B (0.60) | HTR1BCYP1A2CYP2D6ABCB11LMNA | |
| SCHEMBL10694029 | 0.88 | HTR2A (0.49) | HTR1BCYP1A2KDM4EALDH1A1SIGMAR1 | |
| SCHEMBL10690312 | 0.87 | HTR1B (0.51) | HTR1BCYP1A2CYP2D6ABCB11LMNA | |
| SCHEMBL10694635 | 0.86 | HTR1B (0.53) | HTR1BCYP1A2CYP2D6ABCB11LMNA | |
| SCHEMBL10693307 | 0.86 | HTR1B (0.50) | HTR1BCYP1A2KDM4EALDH1A1 | |
| SCHEMBL10694726 | 0.86 | HTR1B (0.46) | HTR1BCYP1A2CYP2D6ABCB11LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | claimed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | claimed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |