Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12930243 | 0.80 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL12109863 | 0.79 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2MAPTHSD17B10 | |
| Hydrochloric Acid SCHEMBL6009383 | 0.78 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL4443518 | 0.77 | ALDH1A1 (0.31) | MAPTALDH1A1 | |
| SCHEMBL23482163 | 0.76 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL1770192 | 0.76 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL28309940 | 0.76 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL12109870 | 0.76 | MAPT (0.55) | NPC1RAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL5543585 | 0.76 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL28015149 | 0.76 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252603-A2 | Adhesives for ceramics and processes for the bonding of ceramics using same | MITSUI SEKIYU KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-01-13 | — | — | EP | disclosed |