Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12930243 | 0.80 | NPC1 (0.57) | NPC1RAB9AMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL12109863 | 0.79 | NPC1 (0.49) | NPC1RAB9AMAPTSMN1; SMN2HSD17B10 | |
| Hydrochloric Acid SCHEMBL6009383 | 0.78 | NPC1 (0.47) | NPC1RAB9AMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL10693986 | 0.76 | NPC1 (0.46) | NPC1RAB9AMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL1770192 | 0.76 | NPC1 (0.46) | NPC1RAB9AMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL5543585 | 0.76 | NPC1 (0.46) | NPC1RAB9AMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL23482163 | 0.76 | NPC1 (0.46) | NPC1RAB9AMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL12109870 | 0.76 | MAPT (0.55) | NPC1RAB9AMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL17281460 | 0.74 | NPC1 (0.72) | NPC1RAB9AMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL19699121 | 0.73 | MAPT (0.49) | NPC1RAB9AMAPTHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |