Acetone

Acetone

SCHEMBL10694002

CC(C)=O.CCC.NCC(=O)CN

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 1/20 0.41
LMNA P02545 4/20 0.40
ALDH1A1 P00352 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
GLRA1 P23415 1/20 0.39
SLC6A9 P48067 1/20 0.39
OR51E2 Q9H255 1/20 0.39
HTR2C P28335 1/20 0.39
KDM4E B2RXH2 2/20 0.39
TRPA1 O75762 1/20 0.37
ALOX15 P16050 2/20 0.35
BLM P54132 1/20 0.35
PMP22 Q01453 1/20 0.35
PAOX Q6QHF9 1/20 0.32
KDM6B O15054 1/20 0.32
KDM5C P41229 1/20 0.32
EGLN1 Q9GZT9 1/20 0.32
PHF8 Q9UPP1 1/20 0.32
KDM2A Q9Y2K7 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1226620 0.82
Acetone SCHEMBL10471041 0.78
Acetone SCHEMBL28304157 0.78
SCHEMBL2882744 0.76
Acetone SCHEMBL8491952 0.74 LMNA (0.50) GABRR1LMNAALDH1A1TDP1GLRA1
Hydrochloric Acid SCHEMBL8387607 0.74
Acetone SCHEMBL3585998 0.74
Hydrochloric Acid SCHEMBL2289332 0.74
Acetone SCHEMBL10835592 0.73
Bromide SCHEMBL23306700 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4786736-A REACTION OF AMINE WITH ALDEHYDE OR KETONE, CYCLIZATION, OXIDATION BASF AKTIENGESELLSCHAFT (DE) 1988-11-22 US disclosed