Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.36 |
| ▸ | PDE4A | P27815 | 3/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.34 |
| ▸ | WNT3A | P56704 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693278 | 0.80 | MEN1 (0.32) | MEN1KMT2AATM | |
| SCHEMBL7342611 | 0.76 | KMT2A (0.39) | HPGDSMN1; SMN2ALDH1A1MAPTMEN1 | |
| SCHEMBL10692241 | 0.75 | HPGD (0.48) | HPGDHSD17B3SMN1; SMN2GAANPC1 | |
| SCHEMBL10691793 | 0.75 | HPGD (0.48) | HPGDHSD17B3SMN1; SMN2GAANPC1 | |
| SCHEMBL9589608 | 0.73 | MEN1 (0.32) | SMN1; SMN2ALDH1A1RAB9AMAPTMEN1 | |
| SCHEMBL10693327 | 0.72 | XDH (0.49) | GAANPC1ALDH1A1RAB9AMAPT | |
| SCHEMBL7341554 | 0.71 | CYP1A2 (0.35) | HPGDSMN1; SMN2GAANPC1ALDH1A1 | |
| SCHEMBL29153730 | 0.65 | HSD17B3 (0.57) | HPGDHSD17B3SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL3924051 | 0.64 | HPGD (0.82) | HPGDALDH1A1MEN1KMT2ACTNNB1 | |
| SCHEMBL20827392 | 0.64 | HPGD (1.00) | HPGDSMN1; SMN2ALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778792-A | Use of 7-acyl benzoxazinones and their derivatives in treating atheromatous disorders | LABORATORIES NEGMA (FR) | 1988-10-18 | — | — | US | disclosed |