Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.49 |
| ▸ | F3 | P13726 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | MAOB | P27338 | 5/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | P4HB | P07237 | 1/20 | 0.44 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693989 | 0.91 | MAOB (0.52) | MAOBMAOACXCL12RELACYP1B1 | |
| SCHEMBL10691942 | 0.80 | XDH (0.49) | XDHF3MAPTRAB9AMAOB | |
| SCHEMBL10694710 | 0.80 | XDH (0.49) | XDHF3MAPTRAB9AMAOB | |
| SCHEMBL9462343 | 0.76 | MAPT (0.46) | F3MAPTRAB9AMAOBMAOA | |
| SCHEMBL9462345 | 0.76 | MAPT (0.46) | F3MAPTRAB9AMAOBMAOA | |
| SCHEMBL10692526 | 0.73 | MGLL (0.37) | RAB9AKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL10691543 | 0.70 | MAOB (0.53) | MAOBMAOAKMT2AMEN1CXCL12 | |
| SCHEMBL10693667 | 0.70 | MAOB (0.53) | MAOBMAOACXCL12RELACYP1B1 | |
| SCHEMBL25223420 | 0.69 | F3 (1.00) | XDHF3MAPTRAB9AMAOB | |
| 4,4'-Dihydroxychalcone SCHEMBL25202156 | 0.69 | F3 (1.00) | XDHF3MAPTRAB9AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778792-A | Use of 7-acyl benzoxazinones and their derivatives in treating atheromatous disorders | LABORATORIES NEGMA (FR) | 1988-10-18 | — | — | US | disclosed |