Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.50 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5610385 | 0.94 | HDAC3 (0.52) | TRPA1MAPTRXFP1HDAC1HDAC2 | |
| SCHEMBL15750893 | 0.85 | ANPEP (0.52) | SMN1; SMN2TDP1 | |
| SCHEMBL8935462 | 0.83 | TRPA1 (0.54) | TRPA1MAPTRXFP1HDAC1HDAC2 | |
| SCHEMBL4775723 | 0.81 | TRPA1 (0.57) | TRPA1MAPTRXFP1S1PR2S1PR4 | |
| SCHEMBL6471773 | 0.81 | TRPA1 (0.57) | TRPA1MAPTRXFP1S1PR2S1PR4 | |
| SCHEMBL10928526 | 0.81 | TRPA1 (0.57) | TRPA1MAPTRXFP1S1PR2S1PR4 | |
| SCHEMBL9782402 | 0.81 | TRPA1 (0.57) | TRPA1MAPTRXFP1S1PR2S1PR4 | |
| SCHEMBL19682101 | 0.81 | TRPA1 (0.67) | TRPA1MAPTRXFP1S1PR2S1PR4 | |
| SCHEMBL15717089 | 0.80 | TRPA1 (0.57) | TRPA1MAPTRXFP1HDAC1HDAC2 | |
| SCHEMBL3170929 | 0.80 | TRPA1 (0.57) | TRPA1MAPTRXFP1HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260689-A2 | Naphtholactam quadratic-acid dyes and optical registration materials containing them | BASF Aktiengesellschaft (DE) | 1988-03-23 | — | — | EP | disclosed |