Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 4/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPN | P05981 | 1/20 | 0.50 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10706853 | 0.91 | CYP2C9 (0.53) | CYP2C9CYP2C19CYP1A2ALOX15MAPT | |
| SCHEMBL10698130 | 0.88 | ALOX15 (0.63) | CYP2C9CYP2C19CYP1A2ALOX15MAPT | |
| SCHEMBL10507688 | 0.85 | CYP2C9 (0.47) | CYP2C9CYP2C19CYP1A2ALOX15MAPT | |
| SCHEMBL10505856 | 0.82 | CYP2C9 (0.45) | CYP2C9CYP2C19CYP1A2ALOX15MAPT | |
| SCHEMBL27236 | 0.82 | CYP2C9 (0.61) | CYP2C9CYP2C19CYP1A2ALOX15MAPT | |
| SCHEMBL29362395 | 0.82 | CYP2C9 (0.61) | CYP2C9CYP2C19CYP1A2ALOX15MAPT | |
| SCHEMBL4595518 | 0.82 | CYP2C9 (0.61) | CYP2C9CYP2C19CYP1A2ALOX15MAPT | |
| SCHEMBL10696728 | 0.82 | CA1 (0.48) | CYP2C9CYP1A2MAPTCA2ALDH1A1 | |
| SCHEMBL10846855 | 0.80 | CYP2C9 (0.42) | CYP2C9CYP2C19CYP1A2ALOX15MAPT | |
| SCHEMBL4811810 | 0.79 | CYP2C9 (0.57) | CYP2C9CYP2C19CYP1A2ALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255478-A1 | Tris(substituted hydroxyphenyl-thio)trithioorthoesters | CIBA-GEIGY AG (CH) | 1988-02-03 | — | — | EP | claimed |
| US-4659762-A | Tris (substituted hydroxyphenylthio) trithioorthoester stabilizers for polymers | CIBA-GEIGY CORPORATION (US) | 1987-04-21 | — | — | US | claimed |
| EP-0255478-A1 | Tris(substituted hydroxyphenyl-thio)trithioorthoesters | CIBA-GEIGY AG (CH) | 1988-02-03 | — | — | EP | disclosed |
| US-4659762-A | Tris (substituted hydroxyphenylthio) trithioorthoester stabilizers for polymers | CIBA-GEIGY CORPORATION (US) | 1987-04-21 | — | — | US | disclosed |