Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694070 | 0.82 | CYP2C9 (0.55) | CA1CA2PTGS1PTGS2ALDH1A1 | |
| SCHEMBL14818254 | 0.78 | CA1 (0.37) | CA1CA2PTGS1PTGS2ESR1 | |
| SCHEMBL12833563 | 0.76 | DAO (0.51) | CA1CA2PTGS1PTGS2ALDH1A1 | |
| SCHEMBL70958 | 0.76 | CA1 (0.55) | CA1CA2PTGS1PTGS2ESR1 | |
| SCHEMBL8668939 | 0.76 | CA1 (0.55) | CA1CA2PTGS1PTGS2ESR1 | |
| SCHEMBL14818262 | 0.75 | ESR1 (0.38) | CA1CA2PTGS1PTGS2ESR1 | |
| SCHEMBL9638241 | 0.74 | MMP2 (0.47) | CA1CA2ESR1ESR2MAPT | |
| SCHEMBL10888518 | 0.74 | CA1 (0.52) | CA1CA2PTGS1PTGS2ESR1 | |
| SCHEMBL10706853 | 0.72 | CYP2C9 (0.53) | CA1CA2PTGS1PTGS2ALDH1A1 | |
| SCHEMBL11871644 | 0.72 | CA1 (0.39) | CA1CA2PTGS1PTGS2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255478-A1 | Tris(substituted hydroxyphenyl-thio)trithioorthoesters | CIBA-GEIGY AG (CH) | 1988-02-03 | — | — | EP | claimed |
| US-4659762-A | Tris (substituted hydroxyphenylthio) trithioorthoester stabilizers for polymers | CIBA-GEIGY CORPORATION (US) | 1987-04-21 | — | — | US | claimed |
| EP-0255478-A1 | Tris(substituted hydroxyphenyl-thio)trithioorthoesters | CIBA-GEIGY AG (CH) | 1988-02-03 | — | — | EP | disclosed |
| US-4659762-A | Tris (substituted hydroxyphenylthio) trithioorthoester stabilizers for polymers | CIBA-GEIGY CORPORATION (US) | 1987-04-21 | — | — | US | disclosed |