Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 11/20 | 0.61 |
| ▸ | KYAT1 | Q16773 | 2/20 | 0.61 |
| ▸ | KYAT3 | Q6YP21 | 2/20 | 0.61 |
| ▸ | GOT1 | P17174 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | EEF2K | O00418 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695532 | 0.80 | TSHR (0.65) | AADATKYAT1KYAT3GOT1KMT2A | |
| SCHEMBL30489285 | 0.80 | TSHR (0.65) | AADATKYAT1KYAT3GOT1KMT2A | |
| SCHEMBL2924606 | 0.79 | KMT2A (0.62) | AADATKYAT1KYAT3GOT1KMT2A | |
| SCHEMBL6435085 | 0.76 | AADAT (0.65) | AADATKYAT1KYAT3GOT1NOTUM | |
| SCHEMBL2955903 | 0.76 | AADAT (1.00) | AADATKYAT1KYAT3GOT1 | |
| SCHEMBL31656272 | 0.76 | AADAT (1.00) | AADATKYAT1KYAT3GOT1 | |
| SCHEMBL3773423 | 0.76 | AADAT (1.00) | AADATKYAT1KYAT3GOT1 | |
| SCHEMBL2132616 | 0.76 | AADAT (1.00) | AADATKYAT1KYAT3GOT1 | |
| Hydrochloric Acid SCHEMBL5134046 | 0.75 | AADAT (0.97) | AADATKYAT1KYAT3GOT1 | |
| Hydrochloric Acid SCHEMBL7421319 | 0.75 | AADAT (0.97) | AADATKYAT1KYAT3GOT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778793-A | CONTROLLING CALCIUM CONCENTRATION-CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-10-18 | — | — | US | disclosed |