SCHEMBL30489285

SCHEMBL30489285

CN1C(=O)C(c2ccccc2)Cc2ccccc21

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.65
KMT2A Q03164 1/20 0.65
ADRA1A P35348 2/20 0.46
DRD2 P14416 2/20 0.46
DRD4 P21917 2/20 0.46
ADRA1D P25100 1/20 0.46
ADRA1B P35368 1/20 0.46
CYP19A1 P11511 1/20 0.45
BRD4 O60885 4/20 0.43
SLC6A2 P23975 2/20 0.43
SLC6A4 P31645 2/20 0.43
ADRA2A P08913 1/20 0.43
ADRA2B P18089 1/20 0.43
ADRA2C P18825 1/20 0.43
HTR2A P28223 1/20 0.43
HTR2C P28335 1/20 0.43
HRH1 P35367 1/20 0.43
HTR2B P41595 1/20 0.43
KCNH2 Q12809 1/20 0.43
AADAT Q8N5Z0 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10695532 1.00 TSHR (0.65) TSHRKMT2AADRA1ADRD2DRD4
SCHEMBL10694512 0.85 CACNA1S (0.51) TSHRKMT2ACYP19A1PYGLPYGM
SCHEMBL10691585 0.82 LMNA (0.49) TSHRKMT2ACYP19A1PYGLPYGM
SCHEMBL10694099 0.80 AADAT (0.61) TSHRKMT2AAADATGOT1KYAT1
Phensuximide SCHEMBL35334 0.79 KMT2A (1.00) TSHRKMT2ACYP19A1BRD4
Phensuximide SCHEMBL35333 0.79 KMT2A (1.00) TSHRKMT2ACYP19A1BRD4
SCHEMBL10688450 0.78 ADRA1A (0.46) TSHRKMT2AADRA1ADRD2DRD4
SCHEMBL9560256 0.77 MAPT (0.56) KMT2AADRA1ADRD2DRD4ADRA1D
SCHEMBL30489337 0.77 MAPT (0.56) KMT2AADRA1ADRD2DRD4ADRA1D
SCHEMBL10692391 0.77 CACNA1S (0.57) TSHRKMT2AADRA1ADRD2DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116043243-B Method for electrochemically synthesizing 3, 4-dihydro-quinolinone compounds 桂林电子科技大学 2025-02-18 CN disclosed
CN-116043243-A Method for electrochemically synthesizing 3, 4-dihydro-quinolinone compounds 桂林电子科技大学 2023-05-02 CN disclosed