Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11039515 | 0.85 | ALDH1A1 (0.76) | ALDH1A1POLBMAPTPKMKMT2A | |
| SCHEMBL27794183 | 0.81 | ALDH1A1 (0.51) | ALDH1A1POLBCYP2C19MAPTPKM | |
| SCHEMBL7444744 | 0.81 | ALDH1A1 (0.54) | ALDH1A1POLBTDP1KMT2ALMNA | |
| SCHEMBL10951249 | 0.80 | ALDH1A1 (0.50) | ALDH1A1POLBMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL10685573 | 0.80 | CYP2C19 (0.50) | ALDH1A1POLBCYP2C19TDP1MAPT | |
| SCHEMBL664917 | 0.77 | ALDH1A1 (0.56) | ALDH1A1POLBCYP2C19MAPTPKM | |
| SCHEMBL27370387 | 0.77 | ALDH1A1 (0.56) | ALDH1A1POLBMAPTPKMKMT2A | |
| SCHEMBL11841515 | 0.77 | ALDH1A1 (0.56) | ALDH1A1POLBMAPTPKMKMT2A | |
| SCHEMBL395369 | 0.77 | ALDH1A1 (0.56) | ALDH1A1POLBMAPTPKMKMT2A | |
| SCHEMBL18053923 | 0.76 | ALDH1A1 (0.55) | ALDH1A1POLBMAPTPKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4720506-A | Immunomodulating agent | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1988-01-19 | — | — | US | disclosed |
| EP-0094599-B1 | USE OF AMINOPHENYLACETIC ACID DERIVATIVES FOR THE MANUFACTURE OF AN IMMUNOMODULATING MEDICAL PREPARATION | MITSUBISHI KASEI CORPORATION (JP) | 1987-04-01 | — | — | EP | disclosed |
| EP-0052296-B1 | GLUTAMINE DERIVATIVES USABLE FOR CURING IMMUNE DISEASES, METHODS FOR THEIR PREPARATION AND COMPOSITIONS COMPRISING SAID DERIVATIVES | MITSUBISHI KASEI CORPORATION (JP) | 1984-06-27 | — | — | EP | disclosed |
| US-4439448-A | IMMUNOMODULATING ACTIVITY | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1984-03-27 | — | — | US | disclosed |
| EP-0094599-A1 | Use of aminophenylacetic acid derivatives for the manufacture of an immunomodulating medical preparation | MITSUBISHI KASEI CORPORATION (JP) | 1983-11-23 | — | — | EP | disclosed |
| EP-0052296-A1 | Glutamine derivatives usable for curing immune diseases, methods for their preparation and compositions comprising said derivatives | MITSUBISHI KASEI CORPORATION (JP) | 1982-05-26 | — | — | EP | disclosed |