Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 6/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.66 |
| ▸ | PAM | P19021 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18354642 | 0.87 | KLK7 (1.00) | KLK7L3MBTL1ALDH1A1NPC1POLB | |
| SCHEMBL11235408 | 0.81 | KLK7 (0.59) | KLK7L3MBTL1ALDH1A1GAAHTT | |
| SCHEMBL10983201 | 0.81 | KLK7 (0.61) | KLK7L3MBTL1ALDH1A1GAAHTT | |
| SCHEMBL9301096 | 0.80 | SMN1; SMN2 (0.72) | ALDH1A1PAMPOLBSMN1; SMN2KMT2A | |
| SCHEMBL5855192 | 0.80 | KLK7 (0.59) | KLK7L3MBTL1ALDH1A1GAAHTT | |
| SCHEMBL1516167 | 0.80 | EPHX2 (1.00) | ALDH1A1GAAHTTEPHX2NPC1 | |
| SCHEMBL11124688 | 0.79 | L3MBTL1 (0.61) | KLK7L3MBTL1ALDH1A1GAAHTT | |
| SCHEMBL10694390 | 0.79 | ALDH1A1 (0.61) | KLK7L3MBTL1ALDH1A1GAAPAM | |
| SCHEMBL20037101 | 0.79 | KLK7 (0.55) | KLK7L3MBTL1ALDH1A1GAAHTT | |
| SCHEMBL18354489 | 0.78 | KLK7 (1.00) | KLK7L3MBTL1ALDH1A1NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | claimed |
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | disclosed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |