Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 5/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.57 |
| ▸ | LCK | P06239 | 1/20 | 0.57 |
| ▸ | FYN | P06241 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
| ▸ | HRAS | P01112 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28391235 | 1.00 | SLC7A5 (0.57) | SLC7A5PTGS1TDP1KDM4EUSP2 | |
| SCHEMBL1070495 | 0.89 | SLC7A5 (0.63) | SLC7A5PTGS1TDP1KDM4EUSP2 | |
| SCHEMBL31453291 | 0.89 | SLC7A5 (0.63) | SLC7A5PTGS1TDP1KDM4EUSP2 | |
| SCHEMBL11440820 | 0.89 | SLC7A5 (0.63) | SLC7A5PTGS1TDP1KDM4EUSP2 | |
| Hydrochloric Acid SCHEMBL4126484 | 0.88 | SLC7A5 (0.61) | SLC7A5PTGS1TDP1KDM4EUSP2 | |
| Hydrochloric Acid SCHEMBL4188588 | 0.88 | SLC7A5 (0.61) | SLC7A5PTGS1TDP1KDM4EUSP2 | |
| SCHEMBL3985411 | 0.86 | SLC7A5 (0.56) | SLC7A5PTGS1TDP1SLC15A1ALDH1A1 | |
| SCHEMBL19115126 | 0.82 | SLC7A5 (0.57) | SLC7A5PTGS1TDP1KDM4EUSP2 | |
| SCHEMBL11445314 | 0.81 | ALOX15 (0.62) | SLC7A5PTGS1TDP1KDM4EUSP2 | |
| SCHEMBL7428506 | 0.81 | LTA4H (0.63) | LTA4HLAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268678-A1 | NOVEL 5-FLUOROURIDINE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-06-01 | — | — | EP | disclosed |