Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4246697 | 0.88 | APP (0.56) | MAOAMAOBSMN1; SMN2APPPPARA | |
| SCHEMBL2000535 | 0.88 | LOXL2 (0.48) | LOXL2IDO1SMN1; SMN2NPSR1APP | |
| SCHEMBL2000944 | 0.86 | LOXL2 (0.46) | LOXL2IDO1SMN1; SMN2NPSR1APP | |
| SCHEMBL8683871 | 0.85 | MGAM (0.46) | LOXL2IDO1SMN1; SMN2NPSR1PPARA | |
| SCHEMBL8683866 | 0.85 | PPARA (0.45) | LOXL2IDO1SMN1; SMN2NPSR1PPARA | |
| SCHEMBL2595772 | 0.74 | SMN1; SMN2 (0.56) | LOXL2IDO1SMN1; SMN2NPSR1PPARA | |
| SCHEMBL2002218 | 0.74 | APP (0.47) | SMN1; SMN2APPPPARAMAPTNPC1 | |
| SCHEMBL11354762 | 0.74 | PTGS1 (0.45) | LOXL2IDO1SMN1; SMN2NPSR1PPARA | |
| SCHEMBL10963156 | 0.74 | MAPT (0.54) | SMN1; SMN2NPSR1PPARAMAPTNPC1 | |
| SCHEMBL4604185 | 0.74 | MAPT (0.76) | LOXL2IDO1SMN1; SMN2APPMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4762830-A | 5-(azolyloxyphenylcarbamoyl)barbituric acid derivatives as anthelmintics | CIBA-GEIGY CORPORATION (US) | 1988-08-09 | — | — | US | disclosed |
| EP-0192180-A1 | 5-(Azolyloxyphenylcarbamoyl)-barbituric acid derivatives as active agents in anthelmics | CIBA-GEIGY AG (CH) | 1986-08-27 | — | — | EP | disclosed |