Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL9176280 | 0.72 | ALDH1A1 (0.40) | NR3C2ALDH1A1TP53LMNASMN1; SMN2 | |
| SCHEMBL10640116 | 0.71 | ALDH1A1 (0.40) | ALDH1A1TSHRGLAKMT2AMAPT | |
| Lactic Acid SCHEMBL10694521 | 0.71 | KMT2A (0.38) | POLBALDH1A1TP53SMN1; SMN2TSHR | |
| SCHEMBL9512119 | 0.69 | NR3C2 (0.51) | POLBNR3C2ALDH1A1TP53TSHR | |
| SCHEMBL4823355 | 0.69 | ALDH1A1 (0.41) | POLBALDH1A1LMNASMN1; SMN2TSHR | |
| Sulfuric Acid SCHEMBL9299588 | 0.69 | ALDH1A1 (0.41) | POLBNR3C2ALDH1A1TP53LMNA | |
| SCHEMBL8649205 | 0.69 | TSHR (0.39) | NR3C2ALDH1A1TP53TSHRGLA | |
| SCHEMBL4446427 | 0.68 | ALDH1A1 (0.46) | ALDH1A1TP53LMNASMN1; SMN2TSHR | |
| Sulfuric Acid SCHEMBL8070181 | 0.68 | NR3C2 (0.47) | NR3C2ALDH1A1TSHRGLAKMT2A | |
| Lactic Acid SCHEMBL21145160 | 0.68 | TP53 (0.50) | ALDH1A1TP53LMNASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258903-A2 | Silver halide photographic light-sensitive material having a reflective base | KONICA CORPORATION (JP) | 1988-03-09 | — | — | EP | disclosed |