Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15894608 | 0.89 | POLB (0.40) | KMT2ATSHRMEN1GFERALDH1A1 | |
| SCHEMBL10381631 | 0.74 | POLB (0.41) | ALDH1A1POLBNR3C1 | |
| Sulfuric Acid SCHEMBL7553547 | 0.74 | POLB (0.38) | KMT2ATSHRMEN1ALDH1A1KDM4E | |
| SCHEMBL8595213 | 0.73 | ALDH1A1 (0.38) | KMT2AMEN1ALDH1A1KDM4ETP53 | |
| SCHEMBL8746609 | 0.73 | ALDH1A1 (0.36) | ALDH1A1POLBNR3C1 | |
| SCHEMBL8649016 | 0.72 | GFER (0.51) | KMT2ATSHRMEN1GFERALDH1A1 | |
| Sulfuric Acid SCHEMBL6006308 | 0.72 | ALDH1A1 (0.34) | ALDH1A1POLBNR3C1 | |
| Sulfuric Acid SCHEMBL6705370 | 0.71 | NR3C1 (0.34) | ALDH1A1POLBNR3C1 | |
| SCHEMBL27584649 | 0.71 | NR3C1 (0.36) | ALDH1A1POLBNR3C1 | |
| Lactic Acid SCHEMBL10694516 | 0.71 | POLB (0.38) | KMT2ATSHRMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258903-A2 | Silver halide photographic light-sensitive material having a reflective base | KONICA CORPORATION (JP) | 1988-03-09 | — | — | EP | disclosed |