Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.85 |
| ▸ | DRD4 | P21917 | 1/20 | 0.85 |
| ▸ | DRD3 | P35462 | 1/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10922109 | 0.99 | DRD2 (0.83) | DRD2DRD4DRD3 | |
| SCHEMBL11163460 | 0.94 | DRD2 (0.88) | DRD2DRD4DRD3 | |
| SCHEMBL9549904 | 0.93 | DRD2 (0.86) | DRD2DRD4DRD3 | |
| SCHEMBL9550034 | 0.93 | DRD2 (0.86) | DRD2DRD4DRD3 | |
| SCHEMBL9549892 | 0.93 | DRD2 (0.86) | DRD2DRD4DRD3 | |
| SCHEMBL9550022 | 0.93 | DRD2 (0.86) | DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL10691937 | 0.93 | DRD2 (0.86) | DRD2DRD4DRD3 | |
| SCHEMBL9549986 | 0.92 | DRD3 (1.00) | DRD2DRD4DRD3 | |
| SCHEMBL9550006 | 0.92 | DRD3 (1.00) | DRD2DRD4DRD3 | |
| SCHEMBL9550045 | 0.92 | DRD2 (0.85) | DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4789683-A | FOR PSYCHOLOGICAL/GASTROINTESTINAL DISORDERS, SCHIZOPHRENIA | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1988-12-06 | — | — | US | claimed |
| EP-0060235-B1 | BENZAMIDO-DERIVATIVES | Astra Läkemedel Aktiebolag (SE) | 1986-01-08 | — | — | EP | claimed |
| EP-0060235-A1 | Benzamido-derivatives | Astra Läkemedel Aktiebolag (SE) | 1982-09-15 | — | — | EP | claimed |
| US-4789683-A | FOR PSYCHOLOGICAL/GASTROINTESTINAL DISORDERS, SCHIZOPHRENIA | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1988-12-06 | — | — | US | disclosed |
| EP-0060235-B1 | BENZAMIDO-DERIVATIVES | Astra Läkemedel Aktiebolag (SE) | 1986-01-08 | — | — | EP | disclosed |
| EP-0060235-A1 | Benzamido-derivatives | Astra Läkemedel Aktiebolag (SE) | 1982-09-15 | — | — | EP | disclosed |