Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.86 |
| ▸ | DRD4 | P21917 | 1/20 | 0.83 |
| ▸ | DRD3 | P35462 | 1/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9549904 | 1.00 | DRD2 (0.86) | DRD2DRD4DRD3 | |
| SCHEMBL9549931 | 0.93 | DRD2 (1.00) | DRD2 | |
| SCHEMBL9549949 | 0.93 | DRD2 (1.00) | DRD2 | |
| SCHEMBL10694519 | 0.93 | DRD2 (0.85) | DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL10922109 | 0.92 | DRD2 (0.83) | DRD2DRD4DRD3 | |
| SCHEMBL9550034 | 0.92 | DRD2 (0.86) | DRD2DRD4DRD3 | |
| SCHEMBL9550022 | 0.92 | DRD2 (0.86) | DRD2DRD4DRD3 | |
| SCHEMBL9549986 | 0.91 | DRD3 (1.00) | DRD2DRD4DRD3 | |
| SCHEMBL9550006 | 0.91 | DRD3 (1.00) | DRD2DRD4DRD3 | |
| SCHEMBL9550077 | 0.90 | DRD2 (0.80) | DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5240957-A | Dopaminergic agent | ASTRA LAKEMEDEL AKTEIBOLAG (SE) | 1993-08-31 | — | — | US | disclosed |
| EP-0156776-B1 | DERIVATIVES OF N-(2-PYRROLIDINYLMETHYL)-BENZAMIDE, PROCESS FOR THEIR PREPARATION, INTERMEDIATES AND A PHARMACEUTICAL PREPARATION | Astra Läkemedel Aktiebolag (SE) | 1989-03-29 | — | — | EP | disclosed |
| EP-0156776-A1 | Derivatives of N-(2-pyrrolidinylmethyl)-benzamide, process for their preparation, intermediates and a pharmaceutical preparation | Astra Läkemedel Aktiebolag (SE) | 1985-10-02 | — | — | EP | disclosed |