Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.40 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695758 | 0.96 | SIGMAR1 (0.41) | HRH1SIGMAR1TEAD1KCNH2ALDH1A1 | |
| SCHEMBL10693222 | 0.78 | KCNH2 (0.35) | KCNH2 | |
| SCHEMBL12891082 | 0.68 | SPHK1 (0.60) | — | |
| SCHEMBL12891081 | 0.68 | SPHK1 (0.60) | — | |
| SCHEMBL20314569 | 0.68 | SIGMAR1 (0.40) | SIGMAR1KCNH2 | |
| SCHEMBL20314562 | 0.68 | CARM1 (0.40) | SIGMAR1TEAD1KCNH2PDE2AMEN1 | |
| SCHEMBL13165310 | 0.67 | SIGMAR1 (0.48) | SIGMAR1KCNH2 | |
| SCHEMBL20314564 | 0.66 | SIGMAR1 (0.43) | SIGMAR1KCNH2 | |
| SCHEMBL12891094 | 0.66 | HDAC8 (0.43) | SIGMAR1KCNH2ALDH1A1 | |
| SCHEMBL4167500 | 0.66 | SIGMAR1 (0.38) | SIGMAR1HTR1DHTR1BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0241429-A2 | Microbicidal silanes | CIBA-GEIGY AG (CH) | 1987-10-14 | — | — | EP | claimed |
| US-4762826-A | FUNGICIDES FOR PLANTS | CIBA-GEIGY CORPORATION (US) | 1988-08-09 | — | — | US | disclosed |
| EP-0241429-A2 | Microbicidal silanes | CIBA-GEIGY AG (CH) | 1987-10-14 | — | — | EP | disclosed |