Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.38 |
| ▸ | DAGLA | Q9Y4D2 | 5/20 | 0.37 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694540 | 0.96 | HRH1 (0.41) | SIGMAR1HRH1TEAD1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10693222 | 0.82 | KCNH2 (0.35) | DAGLAKCNH2 | |
| SCHEMBL8376783 | 0.67 | KMT2A (0.39) | ALDH1A1LMNAHPGDNPSR1 | |
| SCHEMBL13165310 | 0.66 | SIGMAR1 (0.48) | SIGMAR1KCNH2 | |
| SCHEMBL3549526 | 0.66 | HSD11B1 (0.69) | SIGMAR1ALDH1A1 | |
| SCHEMBL20314564 | 0.65 | SIGMAR1 (0.43) | SIGMAR1KCNH2 | |
| SCHEMBL25258805 | 0.64 | TSHR (0.43) | SIGMAR1ALDH1A1HPGDKCNH2 | |
| SCHEMBL10212101 | 0.64 | HRH3 (0.65) | SIGMAR1ALDH1A1KCNH2 | |
| SCHEMBL21732238 | 0.64 | ALDH1A1 (0.38) | ALDH1A1KCNH2 | |
| SCHEMBL9359971 | 0.64 | ADRA2A (0.41) | SIGMAR1TEAD1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0241429-A2 | Microbicidal silanes | CIBA-GEIGY AG (CH) | 1987-10-14 | — | — | EP | claimed |
| US-4762826-A | FUNGICIDES FOR PLANTS | CIBA-GEIGY CORPORATION (US) | 1988-08-09 | — | — | US | disclosed |
| EP-0241429-A2 | Microbicidal silanes | CIBA-GEIGY AG (CH) | 1987-10-14 | — | — | EP | disclosed |