Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 5/20 | 0.40 |
| ▸ | HTR1D | P28221 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | MYB | P10242 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12627551 | 0.74 | SMN1; SMN2 (0.55) | HTR1BSMN1; SMN2LMNAMEN1NPC1 | |
| SCHEMBL10694297 | 0.74 | HTR1B (0.55) | HTR1BSMN1; SMN2LMNAMEN1NPC1 | |
| SCHEMBL12627539 | 0.73 | MCHR1 (0.49) | HTR1BHTR1DSMN1; SMN2LMNAMEN1 | |
| SCHEMBL12627553 | 0.73 | SMN1; SMN2 (0.56) | HTR1BSMN1; SMN2LMNAMEN1NPC1 | |
| SCHEMBL19612488 | 0.71 | SMN1; SMN2 (0.54) | HTR1BSMN1; SMN2LMNAMEN1NPC1 | |
| SCHEMBL10688822 | 0.70 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAMEN1NPC1RAB9A | |
| SCHEMBL12627590 | 0.69 | CNR2 (0.41) | SMN1; SMN2LMNACNR2ALDH1A1L3MBTL1 | |
| SCHEMBL12627518 | 0.69 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNANPC1RAB9ACNR2 | |
| SCHEMBL10691821 | 0.68 | SMN1; SMN2 (0.50) | HTR1BSMN1; SMN2LMNAMEN1NPC1 | |
| SCHEMBL12627515 | 0.68 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAMEN1KMT2ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |