Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10688822 | 0.85 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2MEN1NPC1LMNA | |
| SCHEMBL10690950 | 0.82 | HTR1B (0.50) | HTR1BALDH1A1SMN1; SMN2HTR7MEN1 | |
| SCHEMBL10691821 | 0.82 | SMN1; SMN2 (0.50) | HTR1BALDH1A1SMN1; SMN2MEN1NPC1 | |
| SCHEMBL10695962 | 0.74 | HTR1B (0.62) | HTR1BALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL12627536 | 0.74 | SMN1; SMN2 (0.58) | ALDH1A1SMN1; SMN2MEN1NPC1LMNA | |
| SCHEMBL10694541 | 0.74 | HTR1B (0.40) | HTR1BALDH1A1SMN1; SMN2MEN1NPC1 | |
| SCHEMBL10694635 | 0.73 | HTR1B (0.53) | HTR1BALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL10693837 | 0.73 | HEXA (0.52) | ALDH1A1SMN1; SMN2HTR7MEN1KMT2A | |
| SCHEMBL7618492 | 0.73 | ALDH1A1 (0.81) | HTR1BALDH1A1SMN1; SMN2HTR7MEN1 | |
| SCHEMBL10691295 | 0.73 | HTR1B (0.60) | HTR1BALDH1A1MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |