Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | HTR1B | P28222 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10688822 | 0.88 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAMEN1KMT2ANPC1 | |
| SCHEMBL10694297 | 0.82 | HTR1B (0.55) | SMN1; SMN2HTR1BLMNAMEN1KMT2A | |
| SCHEMBL10693012 | 0.81 | HTR1B (0.42) | HTR1BLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL5988318 | 0.80 | SMN1; SMN2 (0.71) | SMN1; SMN2LMNAMEN1KMT2ANPC1 | |
| SCHEMBL12627536 | 0.76 | SMN1; SMN2 (0.58) | SMN1; SMN2LMNAMEN1KMT2ANPC1 | |
| SCHEMBL10693837 | 0.75 | HEXA (0.52) | SMN1; SMN2MEN1KMT2AALDH1A1CYP2D6 | |
| SCHEMBL12627539 | 0.74 | MCHR1 (0.49) | SMN1; SMN2HTR1BLMNAMEN1KMT2A | |
| SCHEMBL7060496 | 0.73 | L3MBTL1 (0.70) | SMN1; SMN2HTR1BLMNAMEN1KMT2A | |
| SCHEMBL12627502 | 0.73 | MCHR1 (0.49) | SMN1; SMN2HTR1BLMNAMEN1KMT2A | |
| SCHEMBL11018305 | 0.72 | TDP1 (0.50) | SMN1; SMN2HTR1BLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |