Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4207496 | 0.84 | TSHR (0.51) | TSHRKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL7504930 | 0.84 | TSHR (0.48) | TSHRKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL11414115 | 0.84 | ALDH1A1 (0.60) | TSHRKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL10619595 | 0.83 | ALDH1A1 (0.57) | TSHRKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL946547 | 0.83 | TSHR (0.53) | TSHRKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL5932535 | 0.81 | TSHR (0.51) | TSHRKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL6427847 | 0.81 | TSHR (0.49) | TSHRKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL3465939 | 0.80 | TP53 (0.45) | TSHRKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL7498798 | 0.80 | TSHR (0.48) | TSHRKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL12298739 | 0.80 | TSHR (0.45) | TSHRKMT2AMEN1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |
| EP-0020859-A1 | Substituted N-allyl acetanilides, process for their preparation and their use as fungicides | BAYER AG (DE) | 1981-01-07 | — | — | EP | claimed |
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | disclosed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |
| EP-0020859-A1 | Substituted N-allyl acetanilides, process for their preparation and their use as fungicides | BAYER AG (DE) | 1981-01-07 | — | — | EP | disclosed |
| US-3954827-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DT) | 1976-05-04 | — | — | US | disclosed |