SCHEMBL946547

SCHEMBL946547

C=CCN(C(=O)O)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.53
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
ALDH1A1 P00352 3/20 0.47
GLA P06280 2/20 0.47
POLB P06746 1/20 0.46
ESR1 P03372 1/20 0.45
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
HTT P42858 2/20 0.44
PAX8 Q06710 1/20 0.44
TRPM8 Q7Z2W7 1/20 0.44
KDM4E B2RXH2 2/20 0.43
GAA P10253 2/20 0.43
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.43
PKM P14618 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9249486 0.91 ALDH1A1 (0.58) TSHRMEN1KMT2AALDH1A1GLA
SCHEMBL10619595 0.88 ALDH1A1 (0.57) TSHRMEN1KMT2AALDH1A1GLA
SCHEMBL5932535 0.86 TSHR (0.51) TSHRMEN1KMT2AALDH1A1GLA
SCHEMBL9274588 0.85 TSHR (0.44) TSHRMEN1KMT2AALDH1A1GLA
SCHEMBL2577552 0.85 TSHR (0.54) TSHRMEN1KMT2AALDH1A1GLA
SCHEMBL327647 0.85 TSHR (0.50) TSHRMEN1KMT2AALDH1A1GLA
SCHEMBL4237587 0.85 TSHR (0.50) TSHRMEN1KMT2AALDH1A1GLA
SCHEMBL8035000 0.85 TSHR (0.50) TSHRMEN1KMT2AALDH1A1GLA
SCHEMBL5933109 0.85 TSHR (0.50) TSHRMEN1KMT2AALDH1A1GLA
SCHEMBL6765274 0.85 TSHR (0.50) TSHRMEN1KMT2AALDH1A1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2991655-B1 COMPOSITIONS AND METHODS FOR ALTERING SECOND MESSENGER SIGNALING MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2024-04-10 EP claimed
EP-3606528-B1 TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF BROAD INST INC (US) 2023-10-18 EP claimed
CN-116406264-A Compositions comprising phenylalkylcarbamate compounds for the treatment of kca3.1 channel mediated diseases 细胞离子生物医学株式会社 2023-07-07 CN claimed
CN-115996905-A Phenylalkyl carbamate compounds for use in preventing or treating neurodegenerative diseases 生物药品解决方案有限公司 2023-04-21 CN claimed
EP-3649135-B1 SYNTHESIS OF HALICHONDRINS HARVARD COLLEGE (US) 2022-12-28 EP claimed
EP-3172213-B1 MACROCYCLIC KINASE INHIBITORS AND USES THEREOF DANA FARBER CANCER INST INC (US) 2021-09-22 EP claimed
EP-2968211-B1 PHENYL ALKYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY OR EPILEPSY-RELATED SYNDROME BIO PHARM SOLUTIONS CO LTD (KR) 2021-05-12 EP claimed
EP-3092220-B1 VITAMIN C PRODRUGS AND USES THEREOF UNIV FLORIDA (US) 2021-01-20 EP claimed
EP-3171874-B1 IMIDAZOLYL KINASE INHIBITORS AND USES THEREOF DANA FARBER CANCER INST INC (US) 2020-11-18 EP claimed
EP-2016044-B1 PENTACYCLINE DERIVATIVES FOR THE TREATMENT OF INFECTIONS HARVARD COLLEGE (US) 2020-06-10 EP claimed
EP-0520377-A2 A process for the selective preparation of 4,4-methylene-bis-(N-phenylalkylcarbamate) LUCKY LTD. (KR) 1992-12-30 EP claimed
US-4861872-A Alkyl-phenylcarbamate derivative of polysaccharide DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1989-08-29 US claimed
EP-0281951-A1 Alkyl-phenylcarbamate derivative of polysaccharide DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1988-09-14 EP claimed
US-4468245-A N-(2,3-Epoxypropylene)-n-aralkylsulfonamide and herbicidal compositions containing the same MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) 1984-08-28 US claimed
US-4395544-A DYES OR CHEMICAL INTERMEDIATES FOR DYESTUFFS SANDOZ LTD. (CH) 1983-07-26 US claimed
US-4292254-A COSOLVENT, SOLVENT EXTRACTION, AQUEOUS ACID ATLANTIC RICHFIELD COMPANY (US) 1981-09-29 US claimed
US-4290968-A REMOVAL OF AMINE BY-PRODUCTS WITH ION EXCHANGE RESINS ATLANTIC RICHFIELD COMPANY (US) 1981-09-22 US claimed
US-4115378-A TEXTILES BAYER AKTIENGESELLSCHAFT (DE) 1978-09-19 US claimed
US-4085098-A Azo dyes containing a heterocyclic ring having a quaternized nitrogen atom and at least one optionally substituted phenoxyalkyl or naphthyloxyalkyl substituent SANDOZ LTD. (CH) 1978-04-18 US claimed
US-4029490-A BENZYLTHIOLCARBAMATE ISHIHARA SANGYO KAISHA LTD. (JA) 1977-06-14 US claimed