Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 10/20 | 0.69 |
| ▸ | HTR1A | P08908 | 8/20 | 0.69 |
| ▸ | HTR1B | P28222 | 8/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
| ▸ | HTR2A | P28223 | 4/20 | 0.56 |
| ▸ | HTR2B | P41595 | 3/20 | 0.56 |
| ▸ | HTR7 | P34969 | 3/20 | 0.56 |
| ▸ | HTR5A | P47898 | 3/20 | 0.56 |
| ▸ | HTR6 | P50406 | 3/20 | 0.56 |
| ▸ | HTR2C | P28335 | 2/20 | 0.56 |
| ▸ | HTR1E | P28566 | 2/20 | 0.56 |
| ▸ | HTR1F | P30939 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694676 | 1.00 | HTR1D (0.69) | HTR1DHTR1AHTR1BCYP1A2LMNA | |
| Oxalic Acid SCHEMBL10691528 | 0.96 | HTR1D (0.69) | HTR1DHTR1AHTR1BCYP1A2LMNA | |
| Oxalic Acid SCHEMBL10691544 | 0.96 | HTR1D (0.69) | HTR1DHTR1AHTR1BCYP1A2LMNA | |
| Oxalic Acid SCHEMBL10694017 | 0.84 | HTR1A (0.53) | HTR1DHTR1AHTR1BCYP1A2LMNA | |
| Oxalic Acid SCHEMBL10694021 | 0.84 | HTR1A (0.53) | HTR1DHTR1AHTR1BCYP1A2LMNA | |
| SCHEMBL10465885 | 0.83 | HTR1D (0.70) | HTR1DHTR1AHTR1BCYP1A2LMNA | |
| SCHEMBL30058389 | 0.82 | HTR1D (1.00) | HTR1DHTR1AHTR1BCYP1A2LMNA | |
| SCHEMBL4784832 | 0.82 | HTR1D (1.00) | HTR1DHTR1AHTR1BCYP1A2LMNA | |
| SCHEMBL4784837 | 0.82 | HTR1D (1.00) | HTR1DHTR1AHTR1BCYP1A2LMNA | |
| SCHEMBL10690040 | 0.81 | HTR6 (0.63) | HTR1DHTR1AHTR1BCYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4785016-A | VASOCONSTRICTION, MIGRAINES ALKANEAMINO, ALKANE SULFONAMIDE INDOLES | GLAXO GROUP LIMITED (GB) | 1988-11-15 | — | — | US | disclosed |