Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | GUSB | P08236 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257838 | 0.79 | GUSB (0.45) | TAS1R3TAS1R1ALOX5GUSBJAK2 | |
| SCHEMBL9257835 | 0.79 | GUSB (0.45) | TAS1R3TAS1R1ALOX5GUSBJAK2 | |
| SCHEMBL27788036 | 0.78 | HDAC3 (0.56) | ALOX5HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10641662 | 0.78 | HDAC3 (0.56) | ALOX5HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9256654 | 0.72 | GLA (0.53) | TAS1R3TAS1R1ALOX5GUSBJAK2 | |
| SCHEMBL9256644 | 0.72 | GLA (0.53) | TAS1R3TAS1R1ALOX5GUSBJAK2 | |
| SCHEMBL9336383 | 0.71 | ALOX5 (0.47) | TAS1R3TAS1R1ALOX5GUSBJAK2 | |
| SCHEMBL9336376 | 0.71 | ALOX5 (0.47) | TAS1R3TAS1R1ALOX5GUSBJAK2 | |
| SCHEMBL20539210 | 0.71 | GUSB (0.50) | TAS1R3TAS1R1ALOX5GUSBJAK2 | |
| SCHEMBL20539212 | 0.71 | GUSB (0.50) | TAS1R3TAS1R1ALOX5GUSBJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253393-A2 | Methods for treatment of sundamaged human skin with retinoids | Kligman, Albert M. (US) | 1988-01-20 | — | — | EP | claimed |