Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | MASP2 | O00187 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257838 | 1.00 | GUSB (0.45) | GUSBALOX5CYP1A2HSD17B10TAS1R3 | |
| SCHEMBL1126747 | 0.86 | HCAR2 (0.54) | GUSBALOX5HSD17B10TAS1R3TAS1R1 | |
| SCHEMBL12924107 | 0.86 | HCAR2 (0.54) | GUSBALOX5HSD17B10TAS1R3TAS1R1 | |
| SCHEMBL1126746 | 0.86 | HCAR2 (0.54) | GUSBALOX5HSD17B10TAS1R3TAS1R1 | |
| SCHEMBL10694740 | 0.79 | TAS1R3 (0.40) | GUSBALOX5TAS1R3TAS1R1HDAC3 | |
| SCHEMBL9329946 | 0.76 | GUSB (0.54) | GUSBALOX5CYP1A2TAS1R3TAS1R1 | |
| SCHEMBL9329953 | 0.76 | GUSB (0.54) | GUSBALOX5CYP1A2TAS1R3TAS1R1 | |
| SCHEMBL9336383 | 0.76 | ALOX5 (0.47) | GUSBALOX5TAS1R3TAS1R1JAK2 | |
| SCHEMBL9336376 | 0.76 | ALOX5 (0.47) | GUSBALOX5TAS1R3TAS1R1JAK2 | |
| SCHEMBL20539210 | 0.76 | GUSB (0.50) | GUSBALOX5TAS1R3TAS1R1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439932-A | Anticholesterol agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-08 | — | — | US | disclosed |
| US-5306728-A | Substituted amine derivatives having antihyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0448078-A2 | Substituted amine derivatives having anti-hyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-09-25 | — | — | EP | disclosed |