SCHEMBL10694758

SCHEMBL10694758

CCOC(C)Nc1ccccc1CC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
POLB P06746 3/20 0.41
MAPT P10636 3/20 0.40
GAA P10253 2/20 0.40
TAS1R3 Q7RTX0 1/20 0.40
TAS1R1 Q7RTX1 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
GRIN2D O15399 1/20 0.37
GRIN3B O60391 1/20 0.37
GRIN1 Q05586 1/20 0.37
GRIN2A Q12879 1/20 0.37
GRIN2B Q13224 1/20 0.37
GRIN2C Q14957 1/20 0.37
GRIN3A Q8TCU5 1/20 0.37
SIGMAR1 Q99720 1/20 0.37
HDAC3 O15379 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10090580 0.88 ELANE (0.32) ALDH1A1POLBKMT2AL3MBTL1
SCHEMBL7733717 0.87 L3MBTL1 (0.37) ALDH1A1GAAKMT2ASIGMAR1LMNA
SCHEMBL10409255 0.84 ALDH1A1 (0.42) ALDH1A1POLBMAPTGAATAS1R3
SCHEMBL10408183 0.83 POLB (0.43) ALDH1A1POLBMAPTGAATAS1R3
SCHEMBL10408246 0.80 MAPT (0.44) ALDH1A1MAPTGAAHTTLMNA
SCHEMBL30316736 0.79 ALDH1A1 (0.46) ALDH1A1POLBMAPTGAATAS1R3
SCHEMBL8097565 0.79 ALDH1A1 (0.46) ALDH1A1POLBMAPTGAATAS1R3
SCHEMBL19038256 0.79 ALDH1A1 (0.46) ALDH1A1POLBMAPTGAATAS1R3
SCHEMBL28159195 0.79 ALDH1A1 (0.40) ALDH1A1MAPTGAAMEN1KMT2A
SCHEMBL28159197 0.79 ALDH1A1 (0.40) ALDH1A1MAPTGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0257591-A2 Process for preparing diphenylalkene derivatives KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1988-03-02 EP disclosed