Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | POLA1 | P09884 | 1/20 | 0.36 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CDK7 | P50613 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | CCNH | P51946 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27747326 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KDM4ECDK2RXFP1POLA1 | |
| SCHEMBL27658630 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KDM4ECDK2RXFP1POLA1 | |
| SCHEMBL5322835 | 0.80 | ALDH1A1 (0.43) | ALDH1A1KDM4ECDK2RXFP1POLA1 | |
| SCHEMBL11077322 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KDM4ECDK2RXFP1POLA1 | |
| SCHEMBL28231112 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KDM4ECDK2RXFP1POLA1 | |
| SCHEMBL28839814 | 0.77 | ALDH1A1 (0.46) | ALDH1A1KDM4ECDK2RXFP1POLA1 | |
| Iodide SCHEMBL28673351 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KDM4ECDK2RXFP1POLA1 | |
| SCHEMBL28991359 | 0.76 | ALDH1A1 (0.45) | ALDH1A1KDM4ECDK2RXFP1POLA1 | |
| SCHEMBL8332578 | 0.76 | CDK2 (0.50) | ALDH1A1KDM4ECDK2POLA1CDK1 | |
| SCHEMBL27568676 | 0.75 | POLA1 (0.56) | ALDH1A1KDM4ECDK2RXFP1POLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0270885-A1 | Synthesis of purin-9-ylalkylenoxymethyl phosphonic acids | Bristol-Myers Squibb Company (US) | 1988-06-15 | — | — | EP | disclosed |