Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.36 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CDK7 | P50613 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | CCNH | P51946 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325201 | 0.86 | SLC7A5 (0.47) | ALDH1A1RXFP1KDM4ECYP3A4SLC7A5 | |
| SCHEMBL10694875 | 0.80 | ALDH1A1 (0.46) | ALDH1A1RXFP1KDM4ECDK2CCNT1 | |
| SCHEMBL5322828 | 0.78 | CYP3A4 (0.38) | ALDH1A1CYP3A4SLC7A5GRIK1GRIA1 | |
| SCHEMBL8628643 | 0.77 | PDPK1 (0.45) | GRM2POLA1CYP1A2 | |
| SCHEMBL27747326 | 0.77 | ALDH1A1 (0.46) | ALDH1A1RXFP1KDM4ECDK2CCNT1 | |
| SCHEMBL31618832 | 0.75 | ALDH1A1 (0.47) | ALDH1A1RXFP1KDM4ECYP3A4CDK2 | |
| SCHEMBL27658630 | 0.75 | ALDH1A1 (0.50) | ALDH1A1RXFP1KDM4ECYP3A4CDK2 | |
| SCHEMBL21274620 | 0.74 | ALDH1A1 (0.44) | ALDH1A1RXFP1KDM4ECDK2CCNT1 | |
| SCHEMBL23409494 | 0.74 | ALDH1A1 (0.50) | ALDH1A1RXFP1KDM4ECDK2CCNT1 | |
| Iodide SCHEMBL28673351 | 0.73 | ALDH1A1 (0.53) | ALDH1A1RXFP1KDM4ECDK2CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070258899-A1 | Diagnostic and therapeutic agents | KARYON-CTT LTD (FI) | 2007-11-08 | — | — | US | disclosed |
| WO-2007113385-A1 | DIAGNOSTIC AND THERAPEUTIC AGENTS | KARYON-CTT LTD (FI) | 2007-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070258899-A1 | Diagnostic and therapeutic agents | YBX1, MLX, TPX2 | ALDH1A1 4879/4885RXFP1 177/4885KDM4E 2053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.