Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.56 |
| ▸ | PDE6D | O43924 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 2/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2587522 | 0.91 | THRB (0.64) | THRBPDE6DRAB9ATGM2THRA | |
| SCHEMBL14173219 | 0.84 | THRB (0.58) | THRBPDE6DRAB9ATGM2LMNA | |
| SCHEMBL802752 | 0.84 | THRB (0.58) | THRBPDE6DRAB9ATGM2THRA | |
| SCHEMBL2583822 | 0.84 | THRB (0.58) | THRBPDE6DRAB9ATGM2LMNA | |
| SCHEMBL31379798 | 0.84 | THRB (0.58) | THRBPDE6DRAB9ATGM2THRA | |
| SCHEMBL15695636 | 0.84 | THRB (0.58) | THRBPDE6DRAB9ATGM2THRA | |
| SCHEMBL140760 | 0.82 | THRB (0.56) | THRBKMT2AMEN1TDP1KDM4E | |
| SCHEMBL11772755 | 0.82 | THRB (0.56) | THRBPDE6DRAB9ATGM2THRA | |
| SCHEMBL25041907 | 0.80 | THRB (0.55) | THRBKMT2AMEN1HPGDSMN1; SMN2 | |
| SCHEMBL2585540 | 0.80 | THRB (0.55) | THRBLMNAKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4734471-A | Method of curing polyfluoroalkoxyphosphazene | ETHYL CORPORATION (US) | 1988-03-29 | — | — | US | disclosed |
| US-4710549-A | Cross-linked phosphazene polymer | ETHYL CORPORATION (US) | 1987-12-01 | — | — | US | disclosed |