Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 10/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | QPCT | Q16769 | 1/20 | 0.43 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.43 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10688763 | 0.83 | POLB (0.43) | POLBCYP11B1CYP11B2MAPTCYP19A1 | |
| SCHEMBL10688636 | 0.77 | MAPT (0.45) | MAPTSMN1; SMN2HCRTR1TP53ALOX15 | |
| SCHEMBL12145159 | 0.74 | MAPT (0.50) | MAPTSMN1; SMN2HCRTR1TP53ALOX15 | |
| SCHEMBL10690155 | 0.74 | ATP4A (0.55) | MAPTSMN1; SMN2HCRTR1TP53ALOX15 | |
| SCHEMBL10691659 | 0.74 | MAPT (0.50) | POLBMAPTSMN1; SMN2HCRTR1TP53 | |
| SCHEMBL10688657 | 0.73 | MAPT (0.46) | MAPTSMN1; SMN2HCRTR1TP53ALOX15 | |
| SCHEMBL10692844 | 0.72 | KDM4E (0.53) | POLBMAPTSMN1; SMN2HCRTR1TP53 | |
| SCHEMBL11010710 | 0.71 | POLB (0.60) | POLBCYP11B1CYP11B2MAPTSMN1; SMN2 | |
| SCHEMBL12145158 | 0.71 | MAPT (0.55) | MAPTSMN1; SMN2HCRTR1TP53ALOX15 | |
| SCHEMBL8866026 | 0.70 | POLB (1.00) | POLBCYP11B1CYP11B2MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738967-A | Imidazoisoquinoline compounds useful as anti-ulcerative agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | disclosed |
| US-4686227-A | Imidazoisoquinoline compounds useful as anti-ulcerative agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-08-11 | — | — | US | disclosed |
| EP-0165545-A2 | Imidazoisoquinoline compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-12-27 | — | — | EP | disclosed |