Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694924 | 0.72 | POLB (0.53) | KDM4EMAPTKMT2ANPC1MAPK1 | |
| SCHEMBL10688636 | 0.72 | MAPT (0.45) | KDM4EMAPTKMT2ANPC1ALDH1A1 | |
| SCHEMBL10691659 | 0.71 | MAPT (0.50) | KDM4EMAPTKMT2ANPC1ALDH1A1 | |
| SCHEMBL12145159 | 0.71 | MAPT (0.50) | KDM4EMAPTKMT2ANPC1ALDH1A1 | |
| SCHEMBL10690155 | 0.71 | ATP4A (0.55) | KDM4EMAPTKMT2ANPC1ALDH1A1 | |
| SCHEMBL10688657 | 0.70 | MAPT (0.46) | KDM4EMAPTKMT2ANPC1ALDH1A1 | |
| SCHEMBL12145158 | 0.68 | MAPT (0.55) | KDM4EMAPTKMT2ANPC1ALDH1A1 | |
| SCHEMBL10689984 | 0.68 | MAPT (0.44) | KDM4EMAPTKMT2ANPC1ALDH1A1 | |
| SCHEMBL10694933 | 0.65 | ADRA2A (0.50) | KDM4EMAPTKMT2ANPC1ALDH1A1 | |
| SCHEMBL9283836 | 0.64 | DRD2 (0.59) | MAPTTSHRHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738967-A | Imidazoisoquinoline compounds useful as anti-ulcerative agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | disclosed |
| US-4686227-A | Imidazoisoquinoline compounds useful as anti-ulcerative agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-08-11 | — | — | US | disclosed |
| EP-0165545-A2 | Imidazoisoquinoline compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-12-27 | — | — | EP | disclosed |