Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | PLAT | P00750 | 1/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.49 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695177 | 0.91 | TRPV1 (0.59) | TRPV1KDM4ENPC1RAB9APLK1 | |
| SCHEMBL24892110 | 0.90 | KMT2A (0.56) | KDM4ENPC1RAB9AMEN1KMT2A | |
| SCHEMBL30180871 | 0.86 | KMT2A (0.63) | KDM4ENPC1RAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10693788 | 0.85 | NAMPT (0.60) | KDM4ENPC1RAB9AMEN1KMT2A | |
| SCHEMBL10695195 | 0.84 | NAMPT (0.62) | KDM4ENPC1RAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10696567 | 0.84 | MEN1 (0.50) | KDM4ENPC1RAB9AMEN1KMT2A | |
| SCHEMBL10694980 | 0.84 | KMT2A (0.55) | KDM4ENPC1RAB9AMEN1KMT2A | |
| SCHEMBL10696924 | 0.84 | NAMPT (0.65) | KDM4ENPC1RAB9AMEN1KMT2A | |
| SCHEMBL10644987 | 0.83 | NAMPT (0.58) | TRPV1KDM4ENPC1RAB9AMEN1 | |
| SCHEMBL19639325 | 0.83 | MEN1 (0.57) | KDM4ENPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268267-A2 | Guanidinomethylbenzoic acid derivatives, compositions containing the same, processes for preparing the same, and the use of the same in the manufacture of medicaments of therapeutic value | NIPPON HYPOX LABORATORIES INCORPORATED (JP) | 1988-05-25 | — | — | EP | disclosed |