Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 5/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.56 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.55 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.55 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.55 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24892110 | 0.87 | KMT2A (0.56) | NAMPTNPC1RAB9ASMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL10696005 | 0.86 | NPC1 (0.62) | NAMPTNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL4100874 | 0.84 | PRSS1 (0.56) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL10694927 | 0.84 | TRPV1 (0.52) | NAMPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10695195 | 0.84 | NAMPT (0.62) | NAMPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL30180871 | 0.83 | KMT2A (0.63) | NAMPTNPC1RAB9ASMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL10693788 | 0.82 | NAMPT (0.60) | NAMPTNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL10694980 | 0.81 | KMT2A (0.55) | NPC1RAB9ASMN1; SMN2TP53KDM4E | |
| Hydrochloric Acid SCHEMBL10696567 | 0.81 | MEN1 (0.50) | NAMPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL10695177 | 0.81 | TRPV1 (0.59) | NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268267-A2 | Guanidinomethylbenzoic acid derivatives, compositions containing the same, processes for preparing the same, and the use of the same in the manufacture of medicaments of therapeutic value | NIPPON HYPOX LABORATORIES INCORPORATED (JP) | 1988-05-25 | — | — | EP | disclosed |