Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.64 |
| ▸ | HTR2A | P28223 | 2/20 | 0.64 |
| ▸ | HTR7 | P34969 | 2/20 | 0.64 |
| ▸ | HTR6 | P50406 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10688459 | 0.97 | HRH3 (0.64) | HRH3HTR2AHTR7HTR6TDP1 | |
| SCHEMBL10693530 | 0.94 | TDP1 (0.58) | HRH3HTR2AHTR7HTR6TDP1 | |
| SCHEMBL10694755 | 0.86 | MEN1 (0.64) | HRH3HTR2AHTR7HTR6TDP1 | |
| SCHEMBL10687788 | 0.86 | ALDH1A1 (0.53) | TDP1ALDH1A1CYP2D6 | |
| SCHEMBL10694843 | 0.85 | HRH3 (0.50) | HRH3HTR2AHTR7HTR6TDP1 | |
| SCHEMBL10694180 | 0.84 | TDP1 (0.49) | HRH3HTR2AHTR7HTR6TDP1 | |
| SCHEMBL10694866 | 0.81 | MAPK1 (0.55) | HRH3TDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL11162957 | 0.79 | TSHR (0.58) | TDP1 | |
| SCHEMBL8780187 | 0.78 | TDP1 (1.00) | HRH3HTR2AHTR7HTR6TDP1 | |
| SCHEMBL10695772 | 0.78 | SLC6A4 (0.47) | HRH3HTR2AHTR7HTR6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |