Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.55 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.47 |
| ▸ | MMP2 | P08253 | 4/20 | 0.45 |
| ▸ | MMP9 | P14780 | 4/20 | 0.45 |
| ▸ | MMP8 | P22894 | 4/20 | 0.45 |
| ▸ | MMP13 | P45452 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 2/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.42 |
| ▸ | GUSB | P08236 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695790 | 0.85 | MAPT (0.50) | PARP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL10694623 | 0.81 | PARP1 (0.51) | PARP1CHEK2 | |
| SCHEMBL10695465 | 0.81 | PARP1 (0.43) | PARP1CHEK2MMP2MMP9MMP8 | |
| SCHEMBL10695803 | 0.81 | CHEK2 (0.47) | PARP1CHEK2NPC1RAB9ATNKS | |
| Hydrochloric Acid SCHEMBL10695451 | 0.81 | PARP1 (0.49) | PARP1CHEK2MAPTNPC1RAB9A | |
| SCHEMBL10695587 | 0.81 | CHEK2 (0.48) | PARP1CHEK2ALDH1A1 | |
| SCHEMBL6691354 | 0.81 | PARP1 (0.56) | PARP1CHEK2MMP2MMP9MMP8 | |
| SCHEMBL11473548 | 0.81 | PARP1 (0.56) | PARP1CHEK2MMP2MMP9MMP8 | |
| SCHEMBL10695212 | 0.80 | PARP1 (0.52) | PARP1CHEK2MMP2MMP9MMP8 | |
| SCHEMBL10698668 | 0.80 | MAPT (0.50) | PARP1MMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269238-A1 | Imidazoles and their compositions for plant growth regulation | MAY & BAKER LIMITED (GB) | 1988-06-01 | — | — | EP | disclosed |