Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GUSB | P08236 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | CDC7 | O00311 | 1/20 | 0.46 |
| ▸ | GRK6 | P43250 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695090 | 0.85 | PARP1 (0.55) | MAPTHTTSMN1; SMN2RAB9AGUSB | |
| SCHEMBL11472075 | 0.83 | MAPT (0.54) | MAPTMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL10696460 | 0.82 | MAPT (0.55) | MAPTMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL10695152 | 0.81 | PARP1 (0.57) | PARP1PIN1 | |
| SCHEMBL10697513 | 0.81 | PIN1 (0.55) | CDC7GRK6PARP1PIN1 | |
| SCHEMBL10696406 | 0.81 | PIN1 (0.45) | SMN1; SMN2CDC7PARP1ALDH1A1PIN1 | |
| SCHEMBL10697507 | 0.78 | PARP1 (0.60) | MEN1KMT2AHTTL3MBTL1CDC7 | |
| SCHEMBL30823383 | 0.75 | PARP1 (0.78) | PARP1 | |
| SCHEMBL10697405 | 0.74 | CHEK2 (0.43) | PARP1PIN1 | |
| SCHEMBL10695803 | 0.72 | CHEK2 (0.47) | MEN1KMT2ASMN1; SMN2RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269238-A1 | Imidazoles and their compositions for plant growth regulation | MAY & BAKER LIMITED (GB) | 1988-06-01 | — | — | EP | disclosed |
| EP-0261976-A2 | Process for the preparation of copolyesters which show anisotropy when molten | POLYPLASTICS CO. LTD. (JP) | 1988-03-30 | — | — | EP | disclosed |