SCHEMBL10695230

SCHEMBL10695230

Cc1ccccc1C=NC(C#N)=C(N)C#N

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.51
GAA P10253 5/20 0.51
ALDH1A1 P00352 7/20 0.51
KDM4E B2RXH2 6/20 0.51
NPC1 O15118 3/20 0.48
RAB9A P51151 3/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
CASP1 P29466 1/20 0.48
CASP7 P55210 1/20 0.48
HBB P68871 1/20 0.48
L3MBTL1 Q9Y468 3/20 0.42
LMNA P02545 3/20 0.42
HPGD P15428 1/20 0.42
HTT P42858 1/20 0.42
TSHR P16473 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C19 P33261 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10695227 1.00 MAPT (0.51) MAPTGAAALDH1A1KDM4ENPC1
SCHEMBL10695223 1.00 MAPT (0.51) MAPTGAAALDH1A1KDM4ENPC1
SCHEMBL8645205 0.83 GAA (0.52) MAPTGAAALDH1A1KDM4ENPC1
SCHEMBL10694188 0.81 GAA (0.51) MAPTGAAALDH1A1KDM4ENPC1
SCHEMBL10695224 0.81 ALDH1A1 (0.70) MAPTGAAALDH1A1KDM4ENPC1
SCHEMBL10695231 0.81 ALDH1A1 (0.70) MAPTGAAALDH1A1KDM4ENPC1
SCHEMBL10694192 0.81 GAA (0.51) MAPTGAAALDH1A1KDM4ENPC1
SCHEMBL10695228 0.81 ALDH1A1 (0.70) MAPTGAAALDH1A1KDM4ENPC1
SCHEMBL10694197 0.81 GAA (0.51) MAPTGAAALDH1A1KDM4ENPC1
SCHEMBL10696604 0.78 GRIN2D (0.52) MAPTGAAALDH1A1KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0269238-A1 Imidazoles and their compositions for plant growth regulation MAY & BAKER LIMITED (GB) 1988-06-01 EP disclosed