Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 6/20 | 0.43 |
| ▸ | CA2 | P00918 | 6/20 | 0.43 |
| ▸ | CA9 | Q16790 | 5/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22661077 | 0.88 | CA12 (0.50) | GAAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL31679557 | 0.88 | CA12 (0.50) | GAAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL31679558 | 0.86 | CA12 (0.48) | GAAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL10695227 | 0.83 | MAPT (0.51) | GAAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL10694188 | 0.83 | GAA (0.51) | GAAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL10695230 | 0.83 | MAPT (0.51) | GAAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL10694192 | 0.83 | GAA (0.51) | GAAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL10695228 | 0.83 | ALDH1A1 (0.70) | GAAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL10694197 | 0.83 | GAA (0.51) | GAAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL10695223 | 0.83 | MAPT (0.51) | GAAMAPTALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712408-A | Diaminomaleonitrile derivative compounds, polymers, and method of producing same | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1998-01-27 | — | — | US | disclosed |