Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.55 |
| ▸ | HRH2 | P25021 | 9/20 | 0.55 |
| ▸ | HRH1 | P35367 | 9/20 | 0.55 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696993 | 0.86 | KDM4E (0.54) | HRH3HRH2HRH1KCNA5KDM4E | |
| SCHEMBL10695808 | 0.81 | KDM4E (0.48) | HRH3KCNA5KDM4EALDH1A1LMNA | |
| SCHEMBL10697150 | 0.76 | KDM4E (0.56) | HRH3KDM4EALDH1A1LMNA | |
| Oxalic Acid SCHEMBL4495391 | 0.75 | HRH3 (0.56) | HRH3HRH2HRH1KCNA5KDM4E | |
| SCHEMBL4874490 | 0.75 | HRH3 (0.82) | HRH3HRH2HRH1KCNA5KDM4E | |
| Oxalic Acid SCHEMBL10695599 | 0.74 | KDM4E (0.59) | HRH3KDM4EALDH1A1LMNA | |
| SCHEMBL10695019 | 0.74 | KDM4E (0.53) | HRH3KCNA5KDM4EALDH1A1LMNA | |
| SCHEMBL10695426 | 0.74 | KDM4E (0.56) | KCNA5KDM4EALDH1A1LMNA | |
| SCHEMBL227297 | 0.73 | HRH3 (0.85) | HRH3HRH2HRH1 | |
| SCHEMBL15033017 | 0.73 | HRH3 (0.82) | HRH3HRH2HRH1KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252876-A1 | Hydrogenated 1-phenoxyalkylpyridine-3-carboxylic-acid compounds | CIBA-GEIGY AG (CH) | 1988-01-13 | — | — | EP | claimed |
| EP-0252876-A1 | Hydrogenated 1-phenoxyalkylpyridine-3-carboxylic-acid compounds | CIBA-GEIGY AG (CH) | 1988-01-13 | — | — | EP | disclosed |