Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.49 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.49 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | HRH2 | P25021 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695808 | 0.88 | KDM4E (0.48) | KDM4EALDH1A1LMNAHRH3KCNA5 | |
| SCHEMBL10695019 | 0.87 | KDM4E (0.53) | KDM4EALDH1A1LMNAHRH3KCNA5 | |
| SCHEMBL10695529 | 0.86 | HRH3 (0.55) | KDM4EALDH1A1LMNAHRH3KCNA5 | |
| Hydrochloric Acid SCHEMBL10691702 | 0.81 | KCNA5 (0.48) | KDM4EALDH1A1LMNAHRH3KCNA5 | |
| SCHEMBL10697150 | 0.78 | KDM4E (0.56) | KDM4EALDH1A1LMNAHRH3GAA | |
| SCHEMBL8973715 | 0.77 | KDM4E (0.78) | KDM4EALDH1A1LMNAHRH3GAA | |
| SCHEMBL10696841 | 0.77 | HRH3 (0.54) | KDM4EALDH1A1LMNAHRH3KCNA5 | |
| Oxalic Acid SCHEMBL10695599 | 0.76 | KDM4E (0.59) | KDM4EALDH1A1LMNAHRH3GAA | |
| SCHEMBL10700027 | 0.76 | HRH3 (0.53) | KDM4EALDH1A1LMNAHRH3KCNA5 | |
| SCHEMBL10695426 | 0.76 | KDM4E (0.56) | KDM4EALDH1A1LMNAKCNA5GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252876-A1 | Hydrogenated 1-phenoxyalkylpyridine-3-carboxylic-acid compounds | CIBA-GEIGY AG (CH) | 1988-01-13 | — | — | EP | disclosed |