Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696993 | 0.76 | KDM4E (0.54) | KDM4EGAATDP1LMNAALDH1A1 | |
| SCHEMBL10695808 | 0.75 | KDM4E (0.48) | KDM4EGAATDP1SMN1; SMN2LMNA | |
| SCHEMBL19048091 | 0.74 | CYP1A2 (0.61) | KDM4ESMN1; SMN2LMNAALDH1A1KCNA5 | |
| SCHEMBL10695529 | 0.74 | HRH3 (0.55) | KDM4ELMNAALDH1A1KCNA5 | |
| SCHEMBL10697150 | 0.72 | KDM4E (0.56) | KDM4EGAALMNAALDH1A1MEN1 | |
| SCHEMBL10697040 | 0.72 | KDM4E (0.67) | KDM4EGAATDP1SMN1; SMN2LMNA | |
| SCHEMBL3600901 | 0.71 | KDM1A (0.61) | KDM4EKCNA5MEN1KMT2ANPC1 | |
| SCHEMBL3837994 | 0.71 | LTA4H (0.55) | KDM4ESMN1; SMN2ALDH1A1KCNA5MEN1 | |
| Oxalic Acid SCHEMBL10695599 | 0.71 | KDM4E (0.59) | KDM4EGAALMNAALDH1A1MEN1 | |
| SCHEMBL29042805 | 0.71 | CHRNB2 (0.41) | KDM4ESMN1; SMN2ALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252876-A1 | Hydrogenated 1-phenoxyalkylpyridine-3-carboxylic-acid compounds | CIBA-GEIGY AG (CH) | 1988-01-13 | — | — | EP | claimed |
| EP-0252876-A1 | Hydrogenated 1-phenoxyalkylpyridine-3-carboxylic-acid compounds | CIBA-GEIGY AG (CH) | 1988-01-13 | — | — | EP | disclosed |