Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.53 |
| ▸ | RARA | P10276 | 2/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.47 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | RARG | P13631 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL883698 | 0.95 | RARB (0.61) | RARBRARAS1PR1S1PR3CYP3A4 | |
| SCHEMBL19542771 | 0.93 | RARB (0.47) | RARBRARAS1PR1S1PR3CYP3A4 | |
| SCHEMBL30093428 | 0.93 | RARB (0.49) | RARBRARAS1PR1S1PR3CYP3A4 | |
| SCHEMBL876233 | 0.93 | RARB (0.49) | RARBRARAS1PR1S1PR3CYP3A4 | |
| SCHEMBL15581293 | 0.92 | S1PR1 (0.48) | RARBRARAS1PR1S1PR3CYP3A4 | |
| SCHEMBL15581298 | 0.91 | S1PR1 (0.47) | RARBRARAS1PR1S1PR3CYP3A4 | |
| SCHEMBL9513744 | 0.91 | RARB (0.60) | RARBRARAS1PR1S1PR3CYP3A4 | |
| SCHEMBL17614861 | 0.90 | RARB (0.43) | RARBRARAS1PR1S1PR3ALDH1A1 | |
| SCHEMBL18310404 | 0.89 | RARB (0.42) | RARBRARAS1PR1S1PR3ALDH1A1 | |
| SCHEMBL883701 | 0.89 | RARB (0.51) | RARBRARAS1PR1S1PR3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0132377-B1 | COMPOUNDS CONTAINING A FLUOROBIPHENYLYL GROUP AND THEIR USE IN LIQUID CRYSTAL MATERIALS AND DEVICE | The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) | 1988-06-29 | — | — | EP | disclosed |
| US-4696549-A | Compounds containing a fluorobiphenylyl group and their use in liquid crystal material and devices | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1987-09-29 | — | — | US | disclosed |
| US-4594465-A | Compounds containing a fluorobiphenylyl group | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1986-06-10 | — | — | US | disclosed |
| EP-0132377-A2 | Compounds containing a fluorobiphenylyl group and their use in liquid crystal materials and device | The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) | 1985-01-30 | — | — | EP | disclosed |