SCHEMBL883701

SCHEMBL883701

CCCc1ccc(-c2ccc(-c3ccc(OCCOCCOC)cc3)cc2F)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.51
RARA P10276 1/20 0.51
ALDH1A1 P00352 2/20 0.45
MEN1 O00255 1/20 0.45
USP2 O75604 1/20 0.45
LMNA P02545 1/20 0.45
CYP3A4 P08684 1/20 0.45
MAPK1 P28482 1/20 0.45
CASP1 P29466 1/20 0.45
KMT2A Q03164 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
SLCO1B3 Q9NPD5 1/20 0.45
SLCO1B1 Q9Y6L6 1/20 0.45
S1PR1 P21453 4/20 0.45
S1PR3 Q99500 2/20 0.45
PTGES O14684 1/20 0.43
KDM4E B2RXH2 1/20 0.39
RECQL P46063 1/20 0.39
APP P05067 2/20 0.39
CHEK2 O96017 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15105567 0.95 S1PR1 (0.49) RARBRARAALDH1A1MEN1USP2
SCHEMBL15581293 0.91 S1PR1 (0.48) RARBRARAALDH1A1MEN1USP2
SCHEMBL883698 0.91 RARB (0.61) RARBRARAALDH1A1MEN1USP2
SCHEMBL15581298 0.90 S1PR1 (0.47) RARBRARAALDH1A1MEN1USP2
SCHEMBL10695533 0.89 RARB (0.53) RARBRARAALDH1A1MEN1USP2
SCHEMBL30093428 0.87 RARB (0.49) RARBRARAALDH1A1MEN1USP2
SCHEMBL876233 0.87 RARB (0.49) RARBRARAALDH1A1MEN1USP2
SCHEMBL883356 0.87 KDM4E (0.45) RARBRARAALDH1A1MEN1KMT2A
SCHEMBL18724911 0.87 ALDH1A1 (0.44) RARBRARAALDH1A1MEN1USP2
SCHEMBL19542771 0.85 RARB (0.47) RARBRARAALDH1A1MEN1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2619284-B2 LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT MERCK PATENT GMBH (DE) 2022-12-28 EP disclosed
EP-3660130-B1 LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT MERCK PATENT GMBH (DE) 2021-08-04 EP disclosed
EP-3660130-B1 LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT MERCK PATENT GMBH (DE) 2021-08-04 EP disclosed
US-11015121-B2 Liquid crystal displays and liquid crystalline media with homeotropic alignment MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2021-05-25 US disclosed
US-10747061-B2 Display device SAMSUNG DISPLAY CO., LTD. (KR) 2020-08-18 US disclosed
EP-3660130-A1 LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT Merck Patent GmbH (DE) 2020-06-03 EP disclosed
EP-3660130-A1 LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT Merck Patent GmbH (DE) 2020-06-03 EP disclosed
US-20190271886-A1 CURVED LIQUID CRYSTAL DISPLAY DEVICE SAMSUNG DISPLAY CO LTD (KR) 2019-09-05 US disclosed
US-20190256771-A1 LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2019-08-22 US disclosed
US-10338436-B2 Method of manufacturing curved liquid crystal display device and curved liquid crystal display device SAMSUNG DISPLAY CO., LTD. (KR) 2019-07-02 US disclosed
US-9868904-B2 Liquid crystal displays and liquid crystalline media with homeotropic alignment MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2018-01-16 US disclosed
US-9868904-B2 Liquid crystal displays and liquid crystalline media with homeotropic alignment MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2018-01-16 US disclosed
EP-3211059-A1 LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT Merck Patent GmbH (DE) 2017-08-30 EP disclosed
EP-3211059-A1 LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT Merck Patent GmbH (DE) 2017-08-30 EP disclosed
EP-2619284-B1 LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT MERCK PATENT GMBH (DE) 2017-04-12 EP disclosed
EP-2619284-B1 LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT MERCK PATENT GMBH (DE) 2017-04-12 EP disclosed
US-20130182202-A1 LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-07-18 US disclosed
US-20130182202-A1 LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-07-18 US disclosed
US-20130182202-A1 LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-07-18 US disclosed
WO-2012038026-A1 LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT MERCK PATENT GMBH (DE) 2012-03-29 WO disclosed