Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 7/20 | 0.61 |
| ▸ | RARA | P10276 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.52 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695533 | 0.95 | RARB (0.53) | RARBRARACYP3A4ALDH1A1MEN1 | |
| SCHEMBL883701 | 0.91 | RARB (0.51) | RARBRARACYP3A4ALDH1A1MEN1 | |
| SCHEMBL19542771 | 0.89 | RARB (0.47) | RARBRARACYP3A4ALDH1A1MEN1 | |
| SCHEMBL876233 | 0.88 | RARB (0.49) | RARBRARACYP3A4ALDH1A1MEN1 | |
| SCHEMBL30093428 | 0.88 | RARB (0.49) | RARBRARACYP3A4ALDH1A1MEN1 | |
| SCHEMBL15581293 | 0.88 | S1PR1 (0.48) | RARBRARACYP3A4ALDH1A1MEN1 | |
| SCHEMBL15581298 | 0.86 | S1PR1 (0.47) | RARBRARACYP3A4ALDH1A1MEN1 | |
| SCHEMBL15105567 | 0.86 | S1PR1 (0.49) | RARBRARACYP3A4ALDH1A1MEN1 | |
| SCHEMBL9513744 | 0.86 | RARB (0.60) | RARBRARACYP3A4ALDH1A1MEN1 | |
| SCHEMBL15105576 | 0.86 | RARB (0.48) | RARBRARACYP3A4ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3211059-A1 | LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT | Merck Patent GmbH (DE) | 2017-08-30 | — | — | EP | disclosed |
| EP-2619284-B1 | LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2017-04-12 | — | — | EP | disclosed |
| US-20130182202-A1 | LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-07-18 | — | — | US | disclosed |
| WO-2012038026-A1 | LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2012-03-29 | — | — | WO | disclosed |