Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 3/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10765887 | 0.94 | MTNR1A (0.41) | KCNA3MTNR1AMTNR1BKCNH2SIGMAR1 | |
| SCHEMBL10767435 | 0.87 | MTNR1A (0.44) | KCNA3MTNR1AMTNR1BKCNH2SIGMAR1 | |
| SCHEMBL10697193 | 0.80 | CA12 (0.42) | SIGMAR1L3MBTL1MEN1KMT2A | |
| SCHEMBL10695735 | 0.80 | AOC3 (0.36) | KCNA3MEN1KMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL4970515 | 0.79 | KCNH2 (0.50) | MTNR1AMTNR1BKCNH2SIGMAR1SMPD1 | |
| SCHEMBL138431 | 0.79 | KCNH2 (0.50) | MTNR1AMTNR1BKCNH2SIGMAR1KDM4E | |
| SCHEMBL154388 | 0.79 | KCNA3 (0.56) | KCNA3MTNR1AMTNR1BKCNH2SIGMAR1 | |
| SCHEMBL4194250 | 0.77 | KCNH2 (0.48) | MTNR1AMTNR1BKCNH2SIGMAR1SMPD1 | |
| SCHEMBL10830280 | 0.77 | KCNH2 (0.48) | MTNR1AMTNR1BKCNH2SIGMAR1SMPD1 | |
| SCHEMBL17743544 | 0.76 | MTNR1A (0.46) | KCNA3MTNR1AMTNR1BKCNH2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252482-A2 | 7-Acyloxy-6-aminoacyloxypolyoxylabdanes, process for their preparation and their use as medicine | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-01-13 | — | — | EP | disclosed |
| EP-0217372-A2 | Polyoxygenated labdane derivatives, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-08 | — | — | EP | disclosed |